The decision to strip Liverpool of its World Heritage status was made at a United Nations Educational, Scientific and Cultural Organization (UNESCO) meeting in China.
Delegates voted 13 to five in favour of the UNESCO recommendation last month, which stated that the £5 billion Liverpool Waters project and the approval of plans for Everton FC's stadium at Bramley Moore Dock was a "serious deterioration and irreversible loss of attributes".
The city was awarded the title in 2004, in recognition of its historical and architectural impact, particularly the history as a key trading centre during the British Empire and landmarks like the Albert Dock area, which features more grade I-listed buildings than anywhere else in the UK.
But Liverpool has been on the UNESCO danger list since 2012, as the heritage body became increasingly concerned about the development of the city's north docks.
Liverpool mayor Joanne Anderson said: "I’m hugely disappointed and concerned by this decision to delete Liverpool’s World Heritage status, which comes a decade after UNESCO last visited the city to see it with their own eyes".
"Our World Heritage Site has never been in better condition having benefited from hundreds of millions of pounds of investment across dozens of listed buildings and the public realm".
